Xolair side effects: Common, mild, and serious

Xolair, also known as Xolair (omalizumab), is a powerful medication that helps people with moderate-to-severe allergic asthma, chronic hives, and even food allergies. It’s a biologic treatment designed to block the IgE antibodies that trigger allergic responses.

But like any medication, it’s important to understand the possible side effects before starting treatment. At Empower Allergy Treatment, we help patients navigate the benefits and risks of Xolair so they can make informed decisions.

How Xolair Works in the Body

Xolair is an injectable biologic that binds to free IgE in the bloodstream, preventing it from attaching to mast cells and causing an allergic reaction. It’s administered via subcutaneous injection every 2 to 4 weeks, depending on your age, weight, and IgE levels.

Many patients begin to see improvement in symptoms within weeks, but optimal results usually come with ongoing care. Empower provides in-office administration and monitoring to ensure patient safety, especially during the first few doses.

Common and Mild Side Effects of Xolair

Most patients tolerate Xolair well, but mild side effects are common. These can include:

• Injection site reactions like swelling, pain, or redness
• Fatigue or general tiredness after the injection
• Mild headaches
• Joint or muscle aches
• Dizziness or nausea

These symptoms are generally short-lived and manageable with rest, hydration, or over-the-counter medication. Our team discusses all potential side effects during your first visit and continues to monitor your experience closely.

Serious Side Effects and What to Watch For

Although rare, serious side effects can occur. The most severe is anaphylaxis, a potentially life-threatening allergic reaction. Symptoms include:

• Difficulty breathing or wheezing
• Swelling of the face, lips, or throat
• Rapid heartbeat
• Hives or widespread rash

Because of this risk, Xolair carries a black box warning. At Empower, we always observe patients for at least two hours after their first dose to monitor for any adverse reactions. If you ever experience symptoms of a serious allergic reaction, seek emergency medical care immediately.

Long-Term Use: Is Xolair Safe Over Time?

Long-term studies have shown that Xolair is generally safe when monitored by a healthcare provider. No major organ damage or systemic issues have been reported, even after several years of use. Still, regular follow-ups are important.

Our patients are scheduled for periodic evaluations to track symptom control, check for side effects, and assess overall progress. We also help patients integrate Avoidance Planning to reduce exposure to triggers and improve long-term outcomes.

Who Should Not Take Xolair?

Xolair is not for everyone. Patients with a history of severe allergic reactions to biologics or with certain parasitic infections should avoid it. Always inform your allergy specialist if you have:

• A compromised immune system
• A history of anaphylaxis not related to IgE
• Active infections

During your evaluation at Empower, we conduct a full allergy workup and review your medical history to determine if Xolair is a safe option. Alternatives, like Sublingual Immunotherapy, may be recommended if Xolair isn’t right for you.

Empower’s Role in Your Allergy Care

At Empower Allergy Treatment, we focus on evidence-based therapies that are safe, effective, and personalized to your needs. We offer a range of services and programs that include biologic medications, oral challenges, food allergy testing, and customized treatment plans.

Our team is committed to patient education. From your first dose to long-term maintenance, we’re here to answer your questions, adjust your care, and support your progress every step of the way.

Final Thoughts: Weighing Risks vs. Benefits

Like all medications, Xolair comes with risks—but for many patients, the benefits far outweigh them. Improved breathing, fewer hospital visits, and reduced allergic reactions are just some of the life-changing results we’ve seen.

If you’re considering Xolair for asthma, chronic hives, or food allergies, we encourage you to speak with our team. Learn more about us or schedule a consultation today to see if Xolair is right for you.